Frequent nighttime urination (nocturia) is common in those with untreated obstructive sleep apnea (OSA). The cause is thought related to an absence of the normal dip in blood pressure during sleep for those with OSA and/or due to an elevated blood level of atrial natriuretic peptide (ANP). ANP instructs the kidneys to make urine.  

CPAP appears to be an effective treatment for nocturia associated with OSA. 

And, how is heartburn associated with OSA? 

Well, peak gastrin secretion occurs at 10-11 PM. Gastrin is a hormone that stimulates the secretion of gastric acid. It is thought to be your last effort to sterilize your stomach before sleep. 

Esophageal reflux (experienced as heartburn) is common with untreated OSA. Treatment of OSA alleviates reflux.

Obstructive sleep apnea has correlations with:

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Reference:

Zhou, Jiatong, et al. "Association between obstructive sleep apnea syndrome and nocturia: a meta-analysis." Sleep and Breathing 24.4 (2020): 1293-1298.

Margel, David, et al. "Continuous positive airway pressure reduces nocturia in patients with obstructive sleep apnea." Urology 67.5 (2006): 974-977.

Zanation, Adam M., and Brent A. Senior. "The relationship between extraesophageal reflux (EER) and obstructive sleep apnea (OSA)." Sleep medicine reviews 9.6 (2005): 453-458. 

Bonsignore, Maria R., et al. "Obstructive sleep apnea and comorbidities: a dangerous liaison." Multidisciplinary respiratory medicine 14.1 (2019): 1-12.

Disclaimer:

Information in this communication is provided for informational purposes only and is not intended as a substitute for the advice provided by your physician or other healthcare professional. You should not use the information in this communication to diagnose or treat a health problem or disease or prescribe any medication or other treatment.